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[Information] Monoclonal Antibody Production Contract Service "Antibody Craftsman"

[Information] Monoclonal Antibody Production Contract Service "Antibody Craftsman"

It is a selection of antibodies that can distinguish slight differences at the protein terminal!

This document is about the contract service for producing monoclonal antibodies called "Antibody Craftsman," which conducts all selections in vitro without using animal immunity. It allows for binding reactions to be performed with peptides or proteins in their prepared state, without processes such as fragmenting proteins for antigen presentation. As a result, it enables detailed antigen design, such as narrowing down sequences. In this instance, we will introduce the antigen setup and selection method for producing antibodies that can distinguish between fragments before and after cleavage by a certain protease. 【Contents】 ■ Specificity of the antibody ■ Design of the antigen ■ Screening methods ■ Protein antigens and peptide antigens ■ Summary *For more details, please refer to the PDF document or feel free to contact us.

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【Feature 1】Seven characteristics of monoclonal antibody production contract services.

【Feature 1】Seven characteristics of monoclonal antibody production contract services.

The success rate over the past three years boasts over 90% and has been adopted by many pharmaceutical companies.

1. Strategic Selection By using control antigens for strategic selection, it is possible to produce antibodies with special specificities, such as those that recognize the presence or absence of post-translational modifications, or antibodies that recognize common parts of homologous proteins. 2. Production of Antibodies Difficult to Obtain through Animal Immunization Since it does not rely on animal immunization, it is possible to produce antibodies against human or mouse antigens regardless of immune tolerance. Additionally, it is possible to produce antibodies against toxic antigens or immunosuppressive substances. Furthermore, since there is no antigen presentation step, it is also possible to produce antibodies that recognize natural three-dimensional structures. 3. Delivery of Candidate Antibodies in Just 7 Weeks Thanks to automated screening of antibody libraries, automated sequencing, and automated ELISA analysis, the time required from receipt of the antigen to delivery of candidate antibodies (up to 5) is just 7 weeks. For points 4 to 7, please refer to the seven features of the monoclonal antibody production contract service in Feature 2. *For more details, please refer to the PDF document or feel free to contact us.

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Monoclonal Antibody Production Contract Service Prices

Monoclonal Antibody Production Contract Service Prices

The price is based on standard antibody production costs. A precise estimate will be provided after consultation for each project, considering the most efficient process.

Antibody Production Pricing Standard Antibody Production = ¥1,800,000 per antigen Provision of 1 to 5 candidate antibodies (200μg each) from which the customer can select the final antibody, provided at 1mg (Myc-His tagged, ELISA positive). Additional Sequencing = ¥50,000 per 10 clones Additional sequencing for the same antigen. *The standard price includes sequencing for 10 clones. Additional Candidate Antibodies = ¥50,000 per candidate antibody Additional candidate antibodies for customer confirmation against the same antigen (200μg each). *The standard price includes delivery of up to 5 clones. Additional Final Antibody Production = ¥70,000 per 1mg Additional production of final antibodies for the same antigen simultaneously. *The standard price includes delivery of 1 clone (1mg). *For more details, please refer to the PDF document or feel free to contact us.

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